kcnc3-A antibody, Kv3.1 antibody, KShIIID antibody, Kcr2-3 antibody, Kv3.3 antibody, KSHIIID antibody, KV3.3 antibody, SCA13 antibody, kcnc1 antibody, kshiiid antibody, kv3.3 antibody, sca13 antibody, potassium voltage-gated channel subfamily C member 3 antibody, potassium channel, voltage gated Shaw related subfamily C, member 1 S homeolog antibody, potassium voltage gated channel, Shaw-related subfamily, member 3 antibody, potassium channel, voltage gated Shaw related subfamily C, member 3 L homeolog antibody, potassium voltage-gated channel, Shaw-related subfamily, member 3 antibody, KCNC3 antibody, kcnc1.S antibody, Kcnc3 antibody, kcnc3.L antibody
Background
KCNC3 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.Synonyms: KSHIIID, Potassium voltage-gated channel subfamily C member 3, Voltage-gated potassium channel subunit Kv3.3