Kin of IRRE Like 3 (Drosophila) (KIRREL3) (C-Term), (AA 596-626) antibody

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C-Term, AA 596-626
(2), (2), (1), (1), (1), (1), (1)
(20), (19), (16), (1)
(21), (3), (1)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Western Blotting (WB)
(12), (11), (10), (8), (5), (1), (1)
Pubmed 4 references available
Quantity 0.1 mg
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Catalog No. ABIN953085
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Immunogen KLH conjugated synthetic peptide between 596~626 amino acids from the C-terminal region of Human KIRREL3
Specificity This antibody recognizes Human KIRREL3 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name KIRREL3
Background KIRREL3 is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternate names: KIAA1867, KIRREL3, Kin of IRRE-like protein 3, Kin of irregular chiasm-like protein 3, NEPH2, Nephrin-like 2
Molecular Weight 85255 Da
Gene ID 84623
NCBI Accession NP_001155179
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Bhalla, Luo, Buchan et al.: "Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability." in: American journal of human genetics, Vol. 83, Issue 6, pp. 703-13, 2008 (PubMed).

Anney, Lasky-Su, ODúshláine et al.: "Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 8, pp. 1369-78, 2008 (PubMed).

Melzer, Perry, Hernandez et al.: "A genome-wide association study identifies protein quantitative trait loci (pQTLs)." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000072, 2008 (PubMed).

Sellin, Huber, Gerke et al.: "NEPH1 defines a novel family of podocin interacting proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 1, pp. 115-7, 2003 (PubMed).

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