You are viewing an incomplete version of our website. Please click to reload the website as full version.

LNPEP antibody (Leucyl/cystinyl Aminopeptidase) (AA 16-46)

Details for Product anti-LNPEP Antibody No. ABIN953199, Supplier: Log in to see
Antigen
  • fb73h12
  • wu:fb73h12
  • zgc:66103
  • 2010309L07Rik
  • 4732490P18Rik
  • CAP
  • IRAP
  • PLAP
  • gp160
  • vp165
  • P-LAP
  • Vp165
  • LNPEP
Epitope
AA 16-46, N-Term
14
14
6
2
1
1
1
1
1
Reactivity
Human
35
7
3
Host
Rabbit
35
2
2
Clonality
Polyclonal
Conjugate
This LNPEP antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
26
15
14
6
6
4
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of Human LNPEP. Genename: LNPEP
Isotype Ig
Specificity This antibody recognizes Human LNPEP (N-Term).
Purification Affinity Chromatography on Protein A
Alternative Name LNPEP (LNPEP Antibody Abstract)
Background This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].Synonyms: Cystinyl aminopeptidase, EC=3.4.11.3, IRAP, Insulin-regulated membrane aminopeptidase, Insulin-responsive aminopeptidase, LNPEP, Leucyl-cystinyl aminopeptidase, OTASE, Oxytocinase, P-LAP, Placental leucine aminopeptidase
Molecular Weight 117349 Da
Gene ID 4012
NCBI Accession NP_005566
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-LNPEP antibody (Leucyl/cystinyl Aminopeptidase) (AA 16-46) (ABIN953199) Flow cytometric analysis of HL-60 cells using LNPEP Antibody (N-Term) Cat.-No AP52510...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-LNPEP antibody (Leucyl/cystinyl Aminopeptidase) (AA 16-46) (ABIN953199) Formalin fixed, paraffin embedded Human kidney tissue stained with LNPEP Antibody (N-...
Western Blotting (WB) image for anti-LNPEP antibody (Leucyl/cystinyl Aminopeptidase) (AA 16-46) (ABIN953199) Western blot analysis of LNPEP Antibody (N-Term) in HL-60 cell line lysates (35ug/lan...
Background publications Georgiadou, Hearn, Evnouchidou et al.: "Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1584-92, 2010 (PubMed).

Williams, Mistry, Innes et al.: "Expression of AT1R, AT2R and AT4R and their roles in extravillous trophoblast invasion in the human." in: Placenta, Vol. 31, Issue 5, pp. 448-55, 2010 (PubMed).

Landau, Laverrière, Bischof et al.: "Alteration of circulating Placental Leucine Aminopeptidase (P-LAP) activity in preeclampsia." in: Neuro endocrinology letters, Vol. 31, Issue 1, pp. 63-6, 2010 (PubMed).

Johnson, Roten, Dyer et al.: "The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations." in: Human genetics, Vol. 126, Issue 5, pp. 655-66, 2009 (PubMed).

Saveanu, Carroll, Weimershaus et al.: "IRAP identifies an endosomal compartment required for MHC class I cross-presentation." in: Science (New York, N.Y.), Vol. 325, Issue 5937, pp. 213-7, 2009 (PubMed).