Leucine Rich Repeat Containing 26 (LRRC26) (C-Term), (AA 288-319) antibody

Details for Product No. ABIN953215
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Antigen
Synonyms LRRC26, CAPC, bA350O14.10, RP23-132N23.19, RGD1308398
Epitope
C-Term, AA 288-319
(7), (7), (2), (2)
Reactivity
Human
(12), (3)
Host
Rabbit
(12)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(12), (7)
Pubmed 4 references available
Quantity 0.4 mL
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Catalog No. ABIN953215
357.50 $
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Immunogen KLH conjugated synthetic peptide between 288-319 amino acids from the C-terminal region of human LRRC26
Isotype Ig
Specificity This antibody recognizes Human LRRC26 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name LRRC26
Background Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.Synonyms: CAPC, Cytokeratin-associated protein in cancer, Leucine-rich repeat-containing protein 26
Molecular Weight 34857 Da
Gene ID 389816
NCBI Accession NP_001013675
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Egland, Liu, Squires et al.: "High expression of a cytokeratin-associated protein in many cancers." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5929-34, 2006 (PubMed).

Wang, Yoon, Oh et al.: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006 (PubMed).

Anaganti, Hansen, Ha et al.: "Non-AUG translational initiation of a short CAPC transcript generating protein isoform." in: Biochemical and biophysical research communications, Vol. 380, Issue 3, pp. 508-13, 2009 (PubMed).

Yan, Aldrich: "LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium." in: Nature, Vol. 466, Issue 7305, pp. 513-6, 2010 (PubMed).

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