MAD1L1 antibody (N-Term)

Catalog No. ABIN953276

Product Details anti-MAD1L1 Antibody

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Binding Specificity: AA 131-159, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD1L1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human MAD1L1 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 131-159 amino acids from the N-terminal region of human MAD1L1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Alternative Name: MAD1L1 (MAD1L1 Products)

Synonyms: MAD1 antibody, PIG9 antibody, TP53I9 antibody, TXBP181 antibody, AI173502 antibody, AW550425 antibody, Mad1 antibody, zgc:56571 antibody, MAD1-like protein 1 antibody, mitotic arrest deficient 1 like 1 antibody, MAD1 mitotic arrest deficient like 1 antibody, MAD1 mitotic arrest deficient 1-like 1 antibody, deafness, autosomal recessive 19 antibody, MAD1L1 antibody, Mad1l1 antibody, mad1l1 antibody, DFNB19 antibody

Background: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].Synonyms: MAD1-like 1, Mitotic arrest deficient-like protein 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, Tax-binding protein 181

Molecular Weight: 83067 Da

Gene ID: 8379

NCBI Accession: NP_001013858

Pathways: M Phase