MED8 antibody (Middle Region)

Catalog No. ABIN953379

Product Details anti-MED8 Antibody

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Binding Specificity: AA 102-130, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human MED8 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human MED8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MED8

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Alternative Name: MED8 (MED8 Products)

Synonyms: ARC32 antibody, 2210021A15Rik antibody, AB041805 antibody, MNCb-2386 antibody, zgc:76877 antibody, med8-a antibody, mediator complex subunit 8 antibody, mediator complex subunit 8 L homeolog antibody, component of RNA polymerase II antibody, mediator complex subunit Med8 antibody, MED8 antibody, Med8 antibody, med8 antibody, med8.L antibody

Background: This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.Synonyms: Activator-recruited cofactor 32 kDa component, Mediator complex 8, Mediator of RNA polymerase II transcription subunit 8

Molecular Weight: 29080 Da

Gene ID: 112950

NCBI Accession: NP_443109

Pathways: Regulation of Lipid Metabolism by PPARalpha