Myocyte Enhancer Factor 2D (MEF2D) (N-Term), (AA 115-144) antibody

Details for Product No. ABIN953381
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Antigen
Synonyms sl1, sl-1, XMEF2D, MGC145245, C80750
Epitope
N-Term, AA 115-144
(18), (13), (10), (7), (7), (7), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(82), (47), (47), (36), (36), (24), (24)
Host
Rabbit
(73), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(48), (30), (28), (13), (9), (3), (2), (2)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN953381
357.50 $
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Immunogen KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human MEF2D
Isotype Ig
Specificity This antibody reacts to MEF2D.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name MEF2D
Background Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).Synonyms: Myocyte-specific enhancer factor 2D
Molecular Weight 55938 Da
Gene ID 4209
NCBI Accession NP_005911
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors, Neurogenesis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Czubryt, Lamoureux, Ramjiawan et al.: "Regulation of cardiomyocyte Glut4 expression by ZAC1." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16942-50, 2010 (PubMed).

Aude-Garcia, Collin-Faure, Bausinger et al.: "Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression." in: The Biochemical journal, Vol. 430, Issue 2, pp. 237-44, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Jablonski, McAteer, de Bakker et al.: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010 (PubMed).

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