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MOB1A antibody (N-Term)

MOBKL1B Reactivity: Human WB, FACS, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN953473
  • Target See all MOB1A (MOBKL1B) Antibodies
    MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-33, N-Term
    Reactivity
    • 45
    • 30
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 3
    Rabbit
    Clonality
    • 42
    • 3
    Polyclonal
    Conjugate
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This MOB1A antibody is un-conjugated
    Application
    • 20
    • 15
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human MOBKL1B (N-term).
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of Human MOBKL1B
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MOBKL1B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
    Alternative Name
    MOBKL1B (MOBKL1B Products)
    Synonyms
    mob1 antibody, mob4b antibody, MOB1A antibody, MOBK1B antibody, MOB1 antibody, mats1 antibody, mobk1b antibody, mobkl1b antibody, MOBKL1B antibody, wu:fv69d04 antibody, zgc:56189 antibody, C2orf6 antibody, MATS1 antibody, Mob4B antibody, 4022402H07Rik antibody, MOB4B antibody, Mobk1b antibody, Mobkl1b antibody, MOB kinase activator 1A L homeolog antibody, MOB kinase activator 1A antibody, MOB kinase activator 1A pseudogene antibody, mob1a.L antibody, MOB1A antibody, mob1a antibody, LOC712156 antibody, Mob1a antibody
    Background
    Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.Synonyms: C2orf6, MOB4B, MOBK1B, Mob1 alpha, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, Protein Mob4B
    Molecular Weight
    25080 Da
    Gene ID
    55233
    NCBI Accession
    NP_060691
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