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Myosin IE (MYO1E) (AA 227-257), (N-Term) antibody

Details for Product No. ABIN953590, Supplier: Log in to see
Antigen
  • C80397
  • MMIb
  • MYO1E
  • NMI
  • mm1beta
  • myr2
  • FSGS6
  • HuncM-IC
  • MYO1C
  • 2310020N23Rik
  • 9130023P14Rik
  • AA407778
  • myosin-1e
  • myr 3
  • MYR5
  • Myr3
Epitope
N-Term, AA 227-257
18
16
5
5
2
2
1
1
1
Reactivity
Human
35
11
7
Host
Rabbit
39
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
33
26
5
3
3
Supplier
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 227-257aa) of human Myosin-Ie
Isotype Ig
Specificity This antibody recognizes human Myosin-Ie at N-term.
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name Myosin-Ie (MYO1E Antibody Abstract)
Background Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).Synonyms: MYO1C, MYO1E
Molecular Weight 127062 Da
Gene ID 4643
NCBI Accession NP_004989
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Myosin IE (MYO1E) (AA 227-257), (N-Term) antibody (ABIN953590) Western blot analysis in T47D cell line lysates (35ug/lane) using Myosin-Ie Antibody ...
Background publications Feeser, Ignacio, Krendel et al.: "Myo1e binds anionic phospholipids with high affinity." in: Biochemistry, Vol. 49, Issue 43, pp. 9353-60, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Krendel, Osterweil, Mooseker: "Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis." in: FEBS letters, Vol. 581, Issue 4, pp. 644-50, 2007 (PubMed).

Wang, Yoon, Oh et al.: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006 (PubMed).

El Mezgueldi, Tang, Rosenfeld et al.: "The kinetic mechanism of Myo1e (human myosin-IC)." in: The Journal of biological chemistry, Vol. 277, Issue 24, pp. 21514-21, 2002 (PubMed).