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Myosin IE (MYO1E) (N-Term), (AA 227-257) antibody

Details for Product No. ABIN953590
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Antigen
Synonyms C80397, MMIb, MYO1E, NMI, mm1beta, myr2, FSGS6, HuncM-IC, MYO1C, 2310020N23Rik, 9130023P14Rik, AA407778, myosin-1e, myr 3, MYR5, Myr3
Epitope
N-Term, AA 227-257
(8), (7), (2), (1), (1), (1), (1)
Reactivity
Human
(17), (5), (4)
Host
Rabbit
(19), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(21), (15), (5), (5), (5)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN953590
357.50 $
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 227-257aa) of human Myosin-Ie
Specificity This antibody recognizes human Myosin-Ie at N-term.
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name Myosin-Ie
Background Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
Alternate names: MYO1C, MYO1E
Molecular Weight 127062 Da
Gene ID 4643
NCBI Accession NP_004989
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications El Mezgueldi, Tang, Rosenfeld et al.: "The kinetic mechanism of Myo1e (human myosin-IC)." in: The Journal of biological chemistry, Vol. 277, Issue 24, pp. 21514-21, 2002 (PubMed).

Wang, Yoon, Oh et al.: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006 (PubMed).

Krendel, Osterweil, Mooseker: "Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis." in: FEBS letters, Vol. 581, Issue 4, pp. 644-50, 2007 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Feeser, Ignacio, Krendel et al.: "Myo1e binds anionic phospholipids with high affinity." in: Biochemistry, Vol. 49, Issue 43, pp. 9353-60, 2010 (PubMed).

Validation Images
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