Enolase 2 (Gamma, Neuronal) (ENO2) antibody

Details for Product No. ABIN953673
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Antigen
Synonyms ENO2, DKFZp459B1817, eno3, wu:fc09h05, zgc:92418, NSE, AI837106, D6Ertd375e, Eno-2, RNEN3, Lrpb7
Reactivity
Human
(401), (78), (72), (7), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host
Mouse
(249), (168), (12), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(21), (18), (14), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(294), (218), (126), (97), (34), (32), (29), (19), (18), (15), (11), (10), (10), (9), (5), (4), (4), (3), (2), (2)
Pubmed 2 references available
Quantity 1 mL
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Clone E27
Isotype IgG1
Specificity Antibody to NSE reacts with gamma isozyme of Human enolase and does not react with alpha isozyme of human enolase.
Cellular Localization: Cytoplasmic.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Supernatant
Alternative Name Neuron Specific Enolase (ENO2 Antibody Abstract)
Background Enolases are homo- or heterodimers of the three subunits: alpha (46 kDa), beta (44 kDa), and gamma (46 kDa). The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gammasubunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. Gamma-Gamma isozyme of enolase is found at elevated concentrations in small cell lung cancer and pediatric neuroblastoma.Synonyms: 2-phospho-D-glycerate hydro-lyase, ENO2, Enolase 2, Gamma-enolase, NSE, Neural enolase
Gene ID 4747
Research Area Cell/Tissue Markers, Cancer
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Enolase 2 (Gamma, Neuronal) (ENO2) antibody anti-Enolase 2 (Gamma, Neuronal) (ENO2) antibody
Background publications Blumenfeld, Chandhoke, Sagerman et al.: "Neuroendocrine differentiation in gastric adenocarcinomas. An immunohistochemical study." in: Archives of pathology & laboratory medicine, Vol. 120, Issue 5, pp. 478-81, 1996 (PubMed).

Fantini, Johansson: "Neurochemical markers in human cutaneous Merkel cells. An immunohistochemical investigation." in: Experimental dermatology, Vol. 4, Issue 6, pp. 365-71, 1996 (PubMed).

Validation Images
Catalog No. ABIN953673
555.50 $
Plus shipping costs $45.00
Quantity
Price
1 mL
555.50 $

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