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Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 712-742), (C-Term) antibody

Details for Product No. ABIN953690, Supplier: Login to see
Antigen
  • NRF1
  • LCR-F1
  • TCF11
  • AA408798
  • AW212678
  • Lcrf1
  • TCF-11
Epitope
C-Term, AA 712-742
19
15
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
38
13
8
2
1
1
Host
Rabbit
35
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
37
23
2
1
Supplier
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 712-742aa) of human NFE2L1
Isotype Ig
Specificity This antibody recognizes NFE2L1 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name NFE2L1 (NFE2L1 Antibody Abstract)
Background Synonyms: HBZ17, NF-E2-related factor 1, NFE2-related factor 1, NRF1, Nuclear factor erythroid 2-related factor 1, TCF11
Gene ID 4779
NCBI Accession NP_003195
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 712-742), (C-Term) antibody (ABIN953690) Western blot analysis in mouse lung tissue lysates (35ug/lane) using NFE2L1  Antibody...
Background publications Steffen, Seeger, Koch et al.: "Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop." in: Molecular cell, Vol. 40, Issue 1, pp. 147-58, 2010 (PubMed).

Radhakrishnan, Lee, Young et al.: "Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells." in: Molecular cell, Vol. 38, Issue 1, pp. 17-28, 2010 (PubMed).

Wang, Kwok, Chan: "The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 24670-8, 2007 (PubMed).

Newman, Keating: "Comprehensive identification of human bZIP interactions with coiled-coil arrays." in: Science (New York, N.Y.), Vol. 300, Issue 5628, pp. 2097-101, 2003 (PubMed).

Fukuda, Gotoh, Nishida: "Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase." in: The EMBO journal, Vol. 16, Issue 8, pp. 1901-8, 1997 (PubMed).