NR4A3 antibody (C-Term)

Catalog No. ABIN953751

Product Details anti-NR4A3 Antibody

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Binding Specificity: AA 552-582, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR4A3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to NR4A3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 552-582 amino acids from the C-terminal region of human NR4A3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NR4A3

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Alternative Name: NR4A3 (NR4A3 Products)

Synonyms: CHN antibody, CSMF antibody, MINOR antibody, NOR1 antibody, TEC antibody, AI573420 antibody, NOR-1 antibody, Nor1 antibody, NOR-2 antibody, NR4A3 antibody, Nr4a3 antibody, nuclear receptor subfamily 4 group A member 3 antibody, nuclear receptor subfamily 4, group A, member 3 antibody, NR4A3 antibody, Nr4a3 antibody, nr4a3 antibody

Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CHN, CSMF, MINOR, Mitogen-induced nuclear orphan receptor, NOR1, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, TEC

Molecular Weight: 68230 Da

Gene ID: 8013

NCBI Accession: NP_775292

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway