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PNPLA6 antibody (C-Term)
PNPLA6
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PNPLA6 Antibody
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Target
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PNPLA6
(Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
Binding Specificity
All epitopes for PNPLA6 antibodies
AA 960-990, C-Term
Reactivity
All reactivities for PNPLA6 antibodies
Human
Host
All hosts for PNPLA6 antibodies
Rabbit
Clonality
All clonalities for PNPLA6 antibodies
Polyclonal
Conjugate
All conjugates for PNPLA6 antibodies
This PNPLA6 antibody is un-conjugated
Application
All applications for PNPLA6 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human NTE (C-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 960-990 amino acids from the C-terminal region of human NTE Genename: PNPLA6
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PNPLA6
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Target
PNPLA6
(Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
Alternative Name
NTE (PNPLA6 Products )
Synonyms
NTE antibody, NTEMND antibody, SPG39 antibody, iPLA2delta antibody, sws antibody, AI661849 antibody, MSws antibody, Nte antibody, RGD1564611 antibody, wu:fy20f06 antibody, patatin like phospholipase domain containing 6 antibody, patatin-like phospholipase domain containing 6 antibody, PNPLA6 antibody, Pnpla6 antibody, pnpla6 antibody
Background
PNPLA6 is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Synonyms: Neuropathy target esterase, PNPLA6
Molecular Weight
149995 Da
Gene ID
10908
NCBI Accession
NP_001159583
Pathways
Ribonucleoside Biosynthetic Process
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