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HCRTR2 antibody (Hypocretin (Orexin) Receptor 2) (AA 274-304)

Details for Product anti-HCRTR2 Antibody No. ABIN953937, Supplier: Log in to see
Antigen
  • LOC100229747
  • LOC443181
  • hcrtr
  • OX2R
  • mOX2aR
  • mOX2bR
  • mOXR2
  • hypocretin (orexin) receptor 2
  • orexin receptor 2
  • HCRTR2
  • LOC100229747
  • hcrtr2
  • LOC443181
  • Hcrtr2
Epitope
AA 274-304, Middle Region
10
9
8
7
7
4
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
38
15
6
1
1
1
1
Host
Rabbit
22
20
4
Clonality
Polyclonal
Conjugate
This HCRTR2 antibody is un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
42
32
3
2
1
1
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 274-304 amino acids from the Central region of Human Orexin receptor type 2 Genename: HCRTR2
Isotype Ig
Specificity This antibody recognizes Human and Mouse Orexin receptor type 2 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Orexin Receptor Type 2 (HCRTR2 Antibody Abstract)
Background The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.Synonyms: HCRTR2, Hypocretin receptor type 2, Ox2r
Molecular Weight 50694 Da
Gene ID 3062
NCBI Accession NP_001517
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-HCRTR2 antibody (Hypocretin (Orexin) Receptor 2) (AA 274-304) (ABIN953937) Western blot analysis of Orexin receptor type 2 Antibody (Center) in Jurkat cell line...
Western Blotting (WB) image for anti-HCRTR2 antibody (Hypocretin (Orexin) Receptor 2) (AA 274-304) (ABIN953937) Western blot analysis of Orexin receptor type 2 Antibody (Center) in mouse kidney tis...
Background publications Chen, Randeva: "Genomic organization and regulation of the human orexin (hypocretin) receptor 2 gene: identification of alternative promoters." in: The Biochemical journal, Vol. 427, Issue 3, pp. 377-90, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).