PAICS antibody (N-Term)

Catalog No. ABIN953978

Product Details anti-PAICS Antibody

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Binding Specificity: AA 94-123, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAICS antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse PAICS (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 94-123 amino acids from the N-terminal region of human PAICS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAICS

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Alternative Name: PAICS / ADE2 (PAICS Products)

Synonyms: cb293 antibody, sb:cb293 antibody, wu:fa28a05 antibody, GB14262 antibody, DDBDRAFT_0218550 antibody, DDBDRAFT_0230088 antibody, DDB_0218550 antibody, DDB_0230088 antibody, AIRC antibody, AS antibody, ADE2 antibody, ADE2H1 antibody, PAIS antibody, Ade2h1 antibody, Airc antibody, ade2 antibody, airc antibody, paics antibody, pais antibody, 2610511I09Rik antibody, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody, multifunctional protein ADE2 antibody, phosphoribosylaminoimidazole carboxylase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antibody, PAICS antibody, paics antibody, LOC551966 antibody, Tsp_02239a antibody, Tsp_02239 antibody, CNE02500 antibody, purC/E antibody, Paics antibody, paics.2.L antibody

Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AIRC, Multifunctional protein ADE2, PAIS

Molecular Weight: 47079 Da

Gene ID: 10606

NCBI Accession: NP_001072992

Pathways: Chromatin Binding