PAIP2 antibody (N-Term)

Catalog No. ABIN953979

Product Details anti-PAIP2 Antibody

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Binding Specificity: AA 6-34, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human PAIP2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PAIP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2 (PAIP2 Products)

Synonyms: PAIP2A antibody, DKFZp469O1314 antibody, 2310050K10Rik antibody, AU045972 antibody, paip2 antibody, poly(A) binding protein interacting protein 2 antibody, polyadenylate-binding protein-interacting protein 2 antibody, poly(A) binding protein interacting protein 2B L homeolog antibody, PAIP2 antibody, Paip2 antibody, paip2b.L antibody

Background: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.Synonyms: PABP-interacting protein 2, PAIP-2, PAIP2A, Poly(A)-binding protein-interacting protein 2, Polyadenylate-binding protein-interacting protein 2

Molecular Weight: 14984 Da

Gene ID: 51247

NCBI Accession: NP_001028284