PCCA antibody (Middle Region)

Catalog No. ABIN954025

Product Details anti-PCCA Antibody

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Binding Specificity: AA 336-365, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PCCA.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 336-365 amino acids from the Central region of human PCCA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA (PCCA Products)

Synonyms: pcca antibody, zgc:66359 antibody, C79630 antibody, wu:fb92g02 antibody, zgc:100925 antibody, propionyl-CoA carboxylase alpha subunit antibody, propionyl-COA carboxylase alpha chain, mitochondrial antibody, propionyl-CoA carboxylase alpha chain antibody, zinc finger CCCH-type containing 13 antibody, propionyl-Coenzyme A carboxylase, alpha polypeptide antibody, propionyl CoA carboxylase, alpha polypeptide antibody, propionyl-CoA carboxylase alpha subunit L homeolog antibody, PCCA antibody, Pcca antibody, BMEI0800 antibody, pccA antibody, NRI_0781 antibody, zc3h13 antibody, pcca antibody, pcca.L antibody

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: PCCase subunit alpha, Propanoyl-CoA:carbon dioxide ligase subunit alpha, Propionyl-CoA carboxylase alpha chain mitochondrial

Molecular Weight: 80059 Da

Gene ID: 5095

NCBI Accession: NP_000273

Pathways: Monocarboxylic Acid Catabolic Process