PCDHB11 antibody (N-Term)

Catalog No. ABIN954040

Product Details anti-PCDHB11 Antibody

Target: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Binding Specificity: AA 46-76, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects human PCDHB11 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 46-76aa) of human PCDHB11.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHB11

Target: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Alternative Name: PCDHB11 (PCDHB11 Products)

Synonyms: ME2 antibody, PCDH-BETA11 antibody, Pcdhb5E antibody, PcdhbK antibody, protocadherin beta 11 antibody, PCDHB11 antibody, Pcdhb11 antibody

Background: The PCDHB11 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-11, Protocadherin beta-11

Gene ID: 56125

NCBI Accession: NP_061754