PCDHB13 antibody (Middle Region)

Catalog No. ABIN954042

Product Details anti-PCDHB13 Antibody

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Binding Specificity: AA 280-308, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB13 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes PCDHB13.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 280-308aa) of human PCDHB13.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHB13

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Alternative Name: PCDHB13 (PCDHB13 Products)

Synonyms: PCDH-BETA13 antibody, Pcdh3 antibody, Pcdbh6 antibody, PcdhbM antibody, PCDHB13 antibody, protocadherin beta 13 antibody, protocadherin beta 12 antibody, protocadherin beta-8 antibody, PCDHB13 antibody, Pcdhb12 antibody, Pcdhb13 antibody, LOC518612 antibody

Background: The PCDHB13 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-13, Protocadherin beta-13

Gene ID: 56123

NCBI Accession: NP_061756