PGAM2 antibody (N-Term)

Catalog No. ABIN954105

Product Details anti-PGAM2 Antibody

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Binding Specificity: AA 19-49, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse PGAM2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human PGAM2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PGAM2

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Alternative Name: PGAM2 (PGAM2 Products)

Synonyms: zgc:63876 antibody, GSD10 antibody, PGAM-M antibody, PGAMM antibody, D14Mgh1 antibody, Pgmut antibody, phosphoglycerate mutase 2 antibody, phosphoglycerate mutase 2 (muscle) antibody, phosphoglycerate mutase 2 L homeolog antibody, Pgam2 antibody, PGAM2 antibody, pgam2 antibody, pgam2.L antibody

Background: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.Synonyms: BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, PGAM 2, PGAM-M, PGAMM, Phosphoglycerate mutase 2, Phosphoglycerate mutase isozyme M

Molecular Weight: 28766 Da

Gene ID: 5224

NCBI Accession: NP_000281