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Phosphatase and Actin Regulator 3 (PHACTR3) (AA 24-54), (N-Term) antibody

Details for Product No. ABIN954112, Supplier: Log in to see
Antigen
  • h17739
  • scapin1
  • DKFZp459A1919
  • zgc:109967
  • C20orf101
  • H17739
  • SCAPIN1
  • SCAPININ
  • 1500003N10Rik
  • 4930415A02Rik
  • Scapin1
  • Scapinin
  • mKIAA4224
  • scapinin
Epitope
AA 24-54, N-Term
17
15
3
2
1
1
1
1
1
Reactivity
Human
26
5
3
1
1
1
1
1
1
Host
Rabbit
25
2
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
25
17
15
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human PHACTR3
Isotype Ig
Specificity This antibody recognizes Human PHACTR3 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PHACTR3 (PHACTR3 Antibody Abstract)
Background The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.Synonyms: C20orf101, Phosphatase and actin regulator 3, SCAPIN1, Scaffold-associated PP1-inhibiting protein, Scapinin
Molecular Weight 62552 Da
Gene ID 116154
NCBI Accession NP_001186434
Research Area Signaling, Cytoskeleton, Microfilaments
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Phosphatase and Actin Regulator 3 (PHACTR3) (AA 24-54), (N-Term) antibody (ABIN954112) Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tis...
Western Blotting (WB) image for anti-Phosphatase and Actin Regulator 3 (PHACTR3) (AA 24-54), (N-Term) antibody (ABIN954112) Western blot analysis of PHACTR3 Antibody
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Bankovic, Stojsic, Jovanovic et al.: "Identification of genes associated with non-small-cell lung cancer promotion and progression." in: Lung cancer (Amsterdam, Netherlands), Vol. 67, Issue 2, pp. 151-9, 2010 (PubMed).