CSH1 antibody (C-Term)

Catalog No. ABIN954170

Product Details anti-CSH1 Antibody

Target: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Binding Specificity: AA 180-208, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to human CSH1.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 180-208 amino acids from the C-terminal region of human CSH1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CSH1

Target: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Alternative Name: Placental Lactogen (CSH1 Products)

Synonyms: CS-1 antibody, CSA antibody, CSMT antibody, PL antibody, hCS-A antibody, CS-2 antibody, CSB antibody, hCS-B antibody, chorionic somatomammotropin hormone 1 antibody, chorionic somatomammotropin hormone 2 antibody, CSH1 antibody, CSH2 antibody

Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq].Synonyms: CSA, CSH1, CSH2, Choriomammotropin, Chorionic somatomammotropin hormone, HPL

Molecular Weight: 25020 Da

Gene ID: 1442

NCBI Accession: NP_001308

Pathways: Response to Growth Hormone Stimulus