POLR1B antibody (N-Term)

Catalog No. ABIN954237

Product Details anti-POLR1B Antibody

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Binding Specificity: AA 88-117, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human POLR1B (N-term).

Purification: Affinitty Chromatography on Protein A

Immunogen: conjugated synthetic peptide between 88-117 amino acids from the N-terminal region of human POLR1B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POLR1B

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Alternative Name: POLR1B (POLR1B Products)

Synonyms: RPOL-1l antibody, MGC68946 antibody, 128kDa antibody, D630020H17Rik antibody, RPA116 antibody, RPA135 antibody, RPA2 antibody, Rpo1-2 antibody, RNA polymerase I subunit B antibody, polymerase (RNA) I polypeptide B L homeolog antibody, polymerase (RNA) I polypeptide B, 128kDa antibody, polymerase (RNA) I polypeptide B antibody, DNA-directed RNA polymerase I subunit RPA2 antibody, POLR1B antibody, polr1b.L antibody, polr1b antibody, LOC100563266 antibody, LOC100634236 antibody, Polr1b antibody

Background: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).Synonyms: DNA-directed RNA polymerase I 135 kDa polypeptide, DNA-directed RNA polymerase I subunit RPA2, RNA polymerase I subunit 2, RPA135

Molecular Weight: 128229 Da

Gene ID: 84172

NCBI Accession: NP_001131076