PON1 antibody (Middle Region)

Catalog No. ABIN954245

Product Details anti-PON1 Antibody

Target: PON1 (Paraoxonase 1 (PON1))

Binding Specificity: AA 121-149, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human PON1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human PON1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1 (PON1 Products)

Synonyms: esa antibody, pon antibody, pon2 antibody, MGC53915 antibody, MGC89222 antibody, PON1 antibody, ESA antibody, MVCD5 antibody, PON antibody, Pon antibody, paraoxonase 2 antibody, paraoxonase 1 antibody, pon2 antibody, PON1 antibody, Pon1 antibody

Background: The enzyme encoded by this gene is an Arylesterase that mainly hydrolyzes Paroxon to produce p-Nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.Synonyms: A-esterase 1, Aromatic esterase 1, EC=3.1.1.2, EC=3.1.8.1, K-45, PON, PON 1, PON-1, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1

Molecular Weight: 39731 Da

Gene ID: 5444

NCBI Accession: NP_000437