POU3F1 antibody (Internal Region)

Catalog No. ABIN954257

Product Details anti-POU3F1 Antibody

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This POU3F1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-HHALHEDGHE AQLE

Specificity: This antibody recognizes OCT6

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002690.3. Genename: POU3F1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POU3F1

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Alternative Name: POU3F1 / OCT6 (POU3F1 Products)

Synonyms: OCT6 antibody, OTF6 antibody, SCIP antibody, Oct-6 antibody, Oct6 antibody, Otf-6 antibody, Otf6 antibody, Scip antibody, Test1 antibody, Tst-1 antibody, Tst1 antibody, pou50 antibody, wu:fc09d06 antibody, zp-50 antibody, zp50 antibody, zp50pou antibody, Testes-1 antibody, Xlnrl-34 antibody, nrl-22 antibody, nrl-34 antibody, nrl34-A antibody, oct-6 antibody, oct6 antibody, pou3f1 antibody, scip antibody, pou1-A antibody, POU class 3 homeobox 1 antibody, POU domain, class 3, transcription factor 1 antibody, POU class 3 homeobox 1 L homeolog antibody, POU class 3 homeobox 1 S homeolog antibody, POU3F1 antibody, Pou3f1 antibody, pou3f1 antibody, pou3f1.L antibody, pou3f1.S antibody

Background: POU homeodomain proteins are transcriptional regulators that function in various developmental processes (e.g. cell division, differentiation, specification and survival of specific cell types) and participate in the determination of cell fate. The 45 kDa POU transcription factor Oct-6 (also designated SCIP and Tst-1) is expressed by late embryonic Schwann cells of the peripheral nervous system and is also expressed by nonmyelinating Schwann cells in adults. Oct-6 is strongly upregulated in promyelin cells because it is required for the timely differentiation of promyelin cells into myelinating cells. Oct-6 functions during myelination and is required for the proper downregulation of its own gene when myelination proceeds. c-Myc can act synergistically with the POU domain of Oct-6 to produce myelin disease pathogenesis in the mammalian central nervous system.Synonyms: OTF6, Oct-6, Octamer-binding protein 6, Octamer-binding transcription factor 6, POU domain class 3 transcription factor 1, POU domain transcription factor SCIP, SCIP

Gene ID: 5453

NCBI Accession: NP_002690