PSG3 antibody (N-Term)

Catalog No. ABIN954350

Product Details anti-PSG3 Antibody

Target: PSG3 (Pregnancy Specific beta-1-Glycoprotein 3 (PSG3))

Binding Specificity: AA 29-58, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSG3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse PSG3 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 29~58 amino acids from the N-terminal region of human PSG3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PSG3

Target: PSG3 (Pregnancy Specific beta-1-Glycoprotein 3 (PSG3))

Alternative Name: PSG3 (PSG3 Products)

Synonyms: PSG3 antibody, pregnancy specific beta-1-glycoprotein 3 antibody, pregnancy-specific beta-1-glycoprotein 3 antibody, PSG3 antibody, LOC741127 antibody

Background: The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).Synonyms: Carcinoembryonic antigen SG5, PS-beta-G-3, PSBG-3, Pregnancy-specific beta-1-glycoprotein 3, Pregnancy-specific glycoprotein 3

Molecular Weight: 47945 Da

Gene ID: 5671

NCBI Accession: NP_066296