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Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody

Details for Product No. ABIN954371, Supplier: Log in to see
Antigen
  • 1110030G05Rik
  • AU041779
  • Gcap3
  • ACID2
  • PTOV-1
Epitope
AA 28-56, N-Term
19
15
2
1
1
1
Reactivity
Human, Mouse (Murine)
37
19
17
2
Host
Rabbit
38
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
16
14
11
5
1
1
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Immunogen Synthetic peptide - KLH conjugated corresponding to the N-terminal region between 28-56 amino acids of Human PTOV1. Genename: PTOV1.
Isotype Ig
Specificity This antibody recognizes Human and Mouse PTOC1 at N-term.
Purification Protein A column, followed by peptide affinity purification
Alternative Name PTOV1 (PTOV1 Antibody Abstract)
Background PTOV1 may activate transcription. It is Required for nuclear translocation of FLOT1 and promotes cell proliferation.Synonyms: ACID2, Activator interaction domain-containing protein 2, PTOV-1, Prostate tumor-overexpressed gene 1 protein
Molecular Weight 46869 Da
Gene ID 53635
NCBI Accession NP_059128
Research Area Cancer, Cell Cycle, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody (ABIN954371) Immunohistochemistry analysis in human brain tissue (Formalin-fixed, Paraffin-embedde...
Western Blotting (WB) image for anti-Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody (ABIN954371) western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using PTOV1  Ant...
Background publications Morote, Fernández, Alaña et al.: "PTOV1 expression predicts prostate cancer in men with isolated high-grade prostatic intraepithelial neoplasia in needle biopsy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 9, pp. 2617-22, 2008 (PubMed).

Santamaría, Castellanos, Gómez et al.: "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1900-11, 2005 (PubMed).

Mittler, Stühler, Santolin et al.: "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells." in: The EMBO journal, Vol. 22, Issue 24, pp. 6494-504, 2003 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Santamaría, Fernández, Farré et al.: "PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle." in: The American journal of pathology, Vol. 162, Issue 3, pp. 897-905, 2003 (PubMed).