RAD1 antibody (Middle Region)

Catalog No. ABIN954429

Product Details anti-RAD1 Antibody

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Binding Specificity: AA 117-146, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human RAD1 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 117-146 amino acids from the Central region of Human RAD1. Genename: RAD1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RAD1

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Alternative Name: RAD1 (RAD1 Products)

Synonyms: HRAD1 antibody, REC1 antibody, zgc:56502 antibody, zgc:77779 antibody, RAD1 antibody, xrad1 antibody, DKFZp459H1127 antibody, RAD1 checkpoint DNA exonuclease antibody, RAD1 homolog (S. pombe) antibody, RAD1 antibody, Rad1 antibody, rad1 antibody

Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq].Synonyms: Cell cycle checkpoint protein RAD1, DNA repair exonuclease rad1 homolog, REC1, Rad1-like DNA damage checkpoint protein

Molecular Weight: 31827 Da

Gene ID: 5810

NCBI Accession: NP_002844

Pathways: M Phase