RAMP3 antibody (C-Term)

Catalog No. ABIN954447

Product Details anti-RAMP3 Antibody

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse RAMP3 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RAMP3

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3 (RAMP3 Products)

Background: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.Synonyms: CRLR activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, Receptor activity-modifying protein 3

Molecular Weight: 16518 Da

Gene ID: 10268

NCBI Accession: NP_005847

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling