RAN Binding Protein 3 (RANBP3) (N-Term) antibody

Details for Product No. ABIN954449, Supplier: Log in to see
Antigen
  • ranbp3
  • MGC79798
  • 2610024N24Rik
  • AA408221
  • RAN binding protein 3
  • ran binding protein 3
  • RAN binding protein 3-like
  • RANBP3
  • ranbp3
  • Ranbp3
  • RANBP3L
Epitope
N-Term
21
15
13
10
8
4
2
1
1
1
1
1
1
Reactivity
Human
77
21
18
2
2
2
1
1
1
1
Host
Rabbit
52
25
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
58
40
14
10
9
6
4
4
2
1
1
1
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Isotype Ig
Specificity This antibody recognizes Human RANBP3 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name RANBP3 (RANBP3 Antibody Abstract)
Background RANBP3 is a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: Ran-binding protein 3
Molecular Weight 60210 Da
Gene ID 8498
NCBI Accession NP_015559
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-RAN Binding Protein 3 (RANBP3) (N-Term) antibody (ABIN954449) Western blot analysis of RANBP3 Antibody (N-term) in U251 cell line lysates (35ug/lan...
Background publications Dai, Lin, Chang, Feng: "Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling." in: Developmental cell, Vol. 16, Issue 3, pp. 345-57, 2009 (PubMed).

Yoon, Shin, Liu, Ballif, Woo, Gygi, Blenis: "Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport." in: Molecular cell, Vol. 29, Issue 3, pp. 362-75, 2008 (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Hakata, Yamada, Shida: "A multifunctional domain in human CRM1 (exportin 1) mediates RanBP3 binding and multimerization of human T-cell leukemia virus type 1 Rex protein." in: Molecular and cellular biology, Vol. 23, Issue 23, pp. 8751-61, 2003 (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, 2002 (PubMed).