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RBPJL antibody (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like) (AA 15-44)

Details for Product anti-RBPJL Antibody No. ABIN954488, Supplier: Log in to see
Antigen
  • RBP-L
  • RBPJL
  • RBPSUHL
  • rbpsuhl
  • Rbpsuhl
  • SUHL
Epitope
AA 15-44, N-Term
21
15
2
2
2
1
1
1
Reactivity
Human
30
3
3
2
1
1
1
Host
Rabbit
29
1
Clonality
Polyclonal
Conjugate
This RBPJL antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
28
16
16
15
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human RBPJL Genename: RBPJL
Isotype Ig
Specificity This antibody recognizes Human RBPJL (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name RBPJL (RBPJL Antibody Abstract)
Background In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless proteinSynonyms: RBPL, RBPSUHL, Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L
Molecular Weight 56751 Da
Gene ID 11317
NCBI Accession NP_055091
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-RBPJL antibody (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like) (AA 15-44) (ABIN954488) Formalin fixed and paraffin embedded human pancreas tissue reacted with RBPJL Antibod...
Western Blotting (WB) image for anti-RBPJL antibody (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like) (AA 15-44) (ABIN954488) Western blot analysis of  RBPJL Antibody (N-term) in Jurkat cell line lysates (35ug/l...
Background publications Beres, Masui, Swift, Shi, Henke, MacDonald: "PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 117-30, 2005 (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Nakagawa, Koyama, Murata, Morito, Akiyama, Nakamura: "EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue." in: Oncogene, Vol. 19, Issue 2, pp. 210-6, 2000 (PubMed).