RHEB antibody (C-Term)

Catalog No. ABIN954537

Product Details anti-RHEB Antibody

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Binding Specificity: AA 111-142, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHEB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 111-142 amino acids from the C-terminal region of Human RHEB. Genename: RHEB

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RHEB

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Alternative Name: RHEB (RHEB Products)

Synonyms: RHEB2 antibody, RHEB antibody, rheb2 antibody, CG1081 antibody, DReb antibody, Dm Rheb antibody, DmRheb antibody, Dmel\CG1081 antibody, Q9VND8 antibody, RheB antibody, dRheb antibody, rheb antibody, Ras homolog, mTORC1 binding antibody, Ras homolog enriched in brain antibody, ras homolog enriched in brain antibody, Ras homolog, mTORC1 binding L homeolog antibody, RHEB antibody, Rheb antibody, rheb antibody, rheb.L antibody

Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22Synonyms: GTP-binding protein Rheb, RHEB2, Ras homolog enriched in brain

Molecular Weight: 20497 Da

Gene ID: 6009

NCBI Accession: NP_005605

Pathways: RTK Signaling