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Ras Homolog Enriched in Brain Like 1 (RHEBL1) (AA 24-53), (N-Term) antibody

Details for Product No. ABIN954538, Supplier: Login to see
Antigen
  • rhebl1c
  • MGC75978
  • RHEBL1
  • RHEBL1c
  • 1810036J22Rik
Epitope
N-Term, AA 24-53
19
15
4
3
2
2
2
1
1
Reactivity
Human, Mouse (Murine)
20
15
1
1
1
Host
Rabbit
27
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
29
17
Supplier
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Immunogen KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of Human RHEBL1. Genename: RHEBL1
Isotype Ig
Specificity This antibody recognizes Mouse RHEBL1 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name RHEBL1 (RHEBL1 Antibody Abstract)
Background RHEBL1 binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.Synonyms: GTPase RhebL1, Ras homolog enriched in brain like-1 c, Rheb-like protein 1, Rheb2, RhebL1c
Molecular Weight 20682 Da
Gene ID 121268
NCBI Accession NP_653194
Research Area Signaling, DNA/RNA
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Ras Homolog Enriched in Brain Like 1 (RHEBL1) (AA 24-53), (N-Term) antibody (ABIN954538) Western blot analysis of RHEBL1 (N-term) in Mouse lung tissue lysates (35ug/lane). Th...
Background publications Yuan, Shan, Chen et al.: "Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B." in: Molecular biology reports, Vol. 32, Issue 4, pp. 205-14, 2005 (PubMed).

Tee, Blenis, Proud: "Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1." in: FEBS letters, Vol. 579, Issue 21, pp. 4763-8, 2005 (PubMed).

Barrios-Rodiles, Brown, Ozdamar et al.: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Tabancay, Gau, Machado et al.: "Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K." in: The Journal of biological chemistry, Vol. 278, Issue 41, pp. 39921-30, 2003 (PubMed).