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Ribosomal Protein, Large, P0 (RPLP0) (AA 1-30), (N-Term) antibody

Details for Product No. ABIN954604, Supplier: Log in to see
Antigen
  • AP3
  • Ap3
  • Ape
  • CG7490
  • Dmel\\CG7490
  • LP0
  • P0
  • P35
  • PO
  • RLA0
  • RPL P0
  • RpP0
  • RpPO
  • Rplp0
  • l(3)0154
  • l(3)01544
  • p0
  • RPLP0
  • arp
  • fa56b12
  • fb04a12
  • wu:fa56b12
  • wu:fb15a08
  • wu:fk48c12
  • arbp
  • l10e
  • lp0
  • prlp0
  • rpp0
  • L10E
  • PRLP0
  • RPP0
  • 36B4
  • Arbp
  • ARBP
Epitope
N-Term, AA 1-30
18
16
7
2
2
1
1
1
Reactivity
Human
51
16
16
4
2
2
2
1
1
Host
Rabbit
46
5
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
41
29
10
10
2
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human RPLP0 Genename: RPLP0
Isotype Ig
Specificity Recognizes RPLP0 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RPLP0 (RPLP0 Antibody Abstract)
Background RPLP0 was catalyze systhesis by ribosomes, consisting of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This peotein encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. This protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm.Synonyms: 60S acidic ribosomal protein P0, 60S ribosomal protein L10E
Gene ID 6175
NCBI Accession NP_000993
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Ribosomal Protein, Large, P0 (RPLP0) (AA 1-30), (N-Term) antibody (ABIN954604) Western blot analysis of RPLP0 Antibody (N-term) Cat.-No AP53726PU-N in A375 cell lin...
Background publications Vascotto, Fantini, Romanello et al.: "APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1834-54, 2009 (PubMed).

Rinne, Clements, Lamme et al.: "A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes." in: Human molecular genetics, Vol. 17, Issue 13, pp. 1968-77, 2008 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Chang, Chen, Chen et al.: "Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells." in: Oncogene, Vol. 27, Issue 3, pp. 332-8, 2008 (PubMed).

Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).