Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (N-Term), (AA 19-47) antibody

Details for Product No. ABIN954626
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Antigen
Synonyms MGC81290, RPS6KC1, AA682037, B130003F20Rik, C80612, Rpk118, RPK118, humS6PKh1
Epitope
N-Term, AA 19-47
(8), (7), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(16), (15)
Host
Rabbit
(21), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(23), (17), (8), (6), (2), (1)
Pubmed 4 references available
Quantity 0.4 mL
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Catalog No. ABIN954626
357.50 $
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Immunogen KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of Human RPS6KC1. Genename: RPS6KC1
Specificity Recognizes RPS6KC1 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RPS6KC1 / RPK118
Background RPS6KC1 shows homology to the S6 kinase family of serine/threonine kinases. It is a sphingosine kinase-1 (SPHK1)-binding protein that may be involved in transmitting sphingosine 1 phosphate (SPP)-mediated signaling into the cell. Cellular localization: Cytoplasm. Membrane. Also found in some small dot-like or ring- shaped early endosome structures.
Alternate names: 52 kDa ribosomal protein S6 kinase, Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein, Ribosomal protein S6 kinase delta-1, S6K-delta-1, SPHK1-binding protein
Gene ID 26750
NCBI Accession NP_001129610
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hayashi, Okada, Igarashi et al.: "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33319-24, 2002 (PubMed).

Lehner, Semple, Brown et al.: "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region." in: Genomics, Vol. 83, Issue 1, pp. 153-67, 2003 (PubMed).

Liu, Yang, Yuan et al.: "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains." in: Molecules and cells, Vol. 19, Issue 1, pp. 39-45, 2005 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

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