SEPN1 antibody (C-Term)

Catalog No. ABIN954715

Product Details anti-SEPN1 Antibody

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Binding Specificity: AA 416-445, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEPN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SEPN1 (C-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 416-445 amino acids from the C-terminal region of Human SEPN1 Genename: SEPN1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SEPN1

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Alternative Name: Selenoprotein N (SEPN1) (SEPN1 Products)

Synonyms: CFTD antibody, MDRS1 antibody, RSMD1 antibody, RSS antibody, SELN antibody, 1110019I12Rik antibody, AI414492 antibody, SePN antibody, cb686 antibody, wu:fb06g01 antibody, wu:fb73d02 antibody, wu:fv41b08 antibody, zgc:101091 antibody, selenoprotein N antibody, SELENON antibody, Selenon antibody, selenon antibody

Background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Synonyms: SELN

Gene ID: 57190

NCBI Accession: NP_065184

Pathways: Skeletal Muscle Fiber Development