You are viewing an incomplete version of our website. Please click to reload the website as full version.

Septin 2 (SEPT2) (AA 279-309), (C-Term) antibody

Details for Product No. ABIN954726, Supplier: Login to see
Antigen
  • SEPT2
  • sept2
  • Septin-2B
  • diff6
  • hnedd5
  • nedd5
  • pnutl3
  • sept2-B
  • Septin-2
  • DIFF6
  • NEDD5
  • Pnutl3
  • hNedd5
  • AW208991
  • Nedd-5
  • Nedd5
  • mKIAA0158
  • Vesp11
  • wu:fb52g01
  • wu:fb99a01
  • Septin-2A
  • Septin-A
  • septa
  • xlsepta
  • Sep-02
Epitope
C-Term, AA 279-309
25
20
15
5
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
102
41
39
8
2
2
2
Host
Rabbit
68
22
12
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
86
53
16
11
11
9
5
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2
Isotype Ig
Specificity Recognizes SEPT2 (C-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name Septin-2 (SEPT2 Antibody Abstract)
Background Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Synonyms: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT-2, SEPT2, Septin2
Gene ID 4735
NCBI Accession NP_001008491
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Septin 2 (SEPT2) (AA 279-309), (C-Term) antibody (ABIN954726) Western blot analysis of AP53852PU-N SEPT2 Antibody (C-term) Cat.-No AP53852PU-N in N...
Background publications Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Hosgood, Menashe, He et al.: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, 2009 (PubMed).

Mostowy, Danckaert, Tham et al.: "Septin 11 restricts InlB-mediated invasion by Listeria." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11613-21, 2009 (PubMed).

Shen, Vermeulen, Rajaraman et al.: "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." in: Environmental and molecular mutagenesis, Vol. 50, Issue 4, pp. 285-90, 2009 (PubMed).