Septin 2 antibody (C-Term)

Catalog No. ABIN954726

Product Details anti-Septin 2 Antibody

Target: Septin 2 (SEPT2)

Binding Specificity: AA 279-309, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Recognizes SEPT2 (C-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Septin 2

Target: Septin 2 (SEPT2)

Alternative Name: Septin-2 (SEPT2 Products)

Synonyms: DIFF6 antibody, NEDD5 antibody, Pnutl3 antibody, hNedd5 antibody, AW208991 antibody, Nedd-5 antibody, Nedd5 antibody, mKIAA0158 antibody, Vesp11 antibody, nedd5 antibody, wu:fb52g01 antibody, wu:fb99a01 antibody, Septin-2A antibody, Septin-A antibody, diff6 antibody, pnutl3 antibody, sept2 antibody, septa antibody, xlsepta antibody, SEPT2 antibody, Sep-02 antibody, Septin-2B antibody, hnedd5 antibody, sept2-B antibody, Septin-2 antibody, septin 2 antibody, septin 2 L homeolog antibody, septin 2-like antibody, COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain antibody, septin 2 S homeolog antibody, SEPT2 antibody, Sept2 antibody, sept2 antibody, sept2.L antibody, SEPT2L antibody, sepT2 antibody, sept2.S antibody

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Synonyms: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT-2, SEPT2, Septin2

Gene ID: 4735

NCBI Accession: NP_001008491