Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN954734

Serotonin Receptor 2B (HTR2B) (C-Term), (AA 415-442) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
5-HT2B, 5-HT(2B), AJ012488, AV377389, 5-HT-dro2B, 5-HT1BDro, 5-HT[1B]Dro, 5-HT[[1BDro]], 5-HT[[1B]], 5-HT[[1B]]DRO, 5-HT[[1B]]Dro, 5-HT[[dro2B]], 5HT-R2B, 5HT-dro2B, 5HT-dro[[2B]], 5HT1B, 5htdro2b, CG ... show more
Epitope
»Alternatives C-Term, AA 415-442
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN954734
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 415-442 amino acids from the C-terminal region of Human HTR2B Genename: HTR2B
Specificity This antibody recognizes Human and Mouse Serotonin receptor 2B (HTR2B) (C-term).
Purification Affinity Chromatography on Protein A
Background Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alternate names: 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B
Molecular Weight 54298 Da
Gene ID 3357
NCBI Accession NP_000858
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Roberts, Kawut, Krowka et al.: "Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease." in: Gastroenterology, Vol. 139, Issue 1, pp. 130-9.e24, 2010 (PubMed).

Svejda, Kidd, Giovinazzo et al.: "The 5-HT(2B) receptor plays a key regulatory role in both neuroendocrine tumor cell proliferation and the modulation of the fibroblast component of the neoplastic microenvironment." in: Cancer, Vol. 116, Issue 12, pp. 2902-12, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Alternatives for antigen "Serotonin Receptor 2B (HTR2B)", type "Antibodies"
Hosts (39), (4)
Reactivities (40), (4), (1)
Applications (32), (22), (15), (14), (12), (3)
Epitopes (8), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Beacon