Serotonin Receptor 2B (HTR2B) (C-Term), (AA 415-442) antibody

Details for Product No. ABIN954734
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Antigen
Synonyms 5-HT2B, 5HT2B, 5htr2b, HTR2B, 5ht2b, zgc:194094, zgc:194119, AJ012488, AV377389, 5-HT(2B)
Epitope
C-Term, AA 415-442
(8), (7), (7), (6), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(51), (9), (2)
Host
Rabbit
(49), (10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(48), (35), (22), (15), (13), (3), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Request Want additional data for this product?

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Catalog No. ABIN954734
357.50 $
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Immunogen KLH conjugated synthetic peptide between 415-442 amino acids from the C-terminal region of Human HTR2B Genename: HTR2B
Specificity This antibody recognizes Human and Mouse Serotonin receptor 2B (HTR2B) (C-term).
Purification Affinity Chromatography on Protein A
Background Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alternate names: 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B
Molecular Weight 54298 Da
Gene ID 3357
NCBI Accession NP_000858
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Roberts, Kawut, Krowka et al.: "Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease." in: Gastroenterology, Vol. 139, Issue 1, pp. 130-9.e24, 2010 (PubMed).

Svejda, Kidd, Giovinazzo et al.: "The 5-HT(2B) receptor plays a key regulatory role in both neuroendocrine tumor cell proliferation and the modulation of the fibroblast component of the neoplastic microenvironment." in: Cancer, Vol. 116, Issue 12, pp. 2902-12, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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