Serotonin Receptor 3A antibody (N-Term)

Catalog No. ABIN954735

Product Details anti-Serotonin Receptor 3A Antibody

Target: Serotonin Receptor 3A (HTR3A)

Binding Specificity: AA 37-66, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Serotonin receptor 3A (HTR3A) (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of Human Serotonin receptor 3A (HTR3A)

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Abstract: HTR3A Products

Synonyms: MGC52789 antibody, HTR3A antibody, 5-HT3 antibody, 5HT3R antibody, HTR3 antibody, 5-HT-3 antibody, 5-HT3A antibody, 5-HT3R antibody, 5HT3 antibody, Htr3 antibody, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog antibody, 5-hydroxytryptamine receptor 3A antibody, 5-hydroxytryptamine (serotonin) receptor 3A antibody, htr3a.L antibody, HTR3A antibody, Htr3a antibody

Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

Molecular Weight: 55280 Da

Gene ID: 3359

NCBI Accession: NP_000860

Pathways: Synaptic Membrane