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Serotonin Receptor 7 (HTR7) (AA 404-433), (C-Term) antibody

Details for Product No. ABIN954739, Supplier: Log in to see
Antigen
  • 5-HT-dro
  • 5-HT-dro1
  • 5-HT7Dro
  • 5-HT[7]Dro
  • 5-HT[[7Dro]]
  • 5-HT[[7]]
  • 5-HT[[7]]Dro
  • 5-HT[[dro1]]
  • 5-HTdro1
  • 5HT-7
  • 5HT-R1
  • 5HT-dro
  • 5HT-dro1
  • 5HT[[7Dro]]
  • 5htdror
  • CG12073
  • DRO1
  • Dm5HTdro1
  • Dmel\\CG12073
  • 5-HT7
  • 5Ht7
  • 5HT7
  • htr7-A
Alternatives
anti-Human Serotonin Receptor 7 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
C-Term, AA 404-433
42
14
13
3
2
2
1
1
1
1
1
1
Reactivity
Human
76
12
11
6
5
2
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
67
13
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
45
37
15
14
10
2
2
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of Human Serotonin receptor 7 (HTR7).
Isotype Ig
Specificity This antibody recognizes Human Serotonin receptor 7 (HTR7) (C-term).
Purification Protein A column, followed by peptide affinity purification
Background The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.Synonyms: 5-HT-7, 5-hydroxytryptamine receptor 7, 5HT7
Molecular Weight 53555 Da
Gene ID 3363
NCBI Accession NP_000863
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Serotonin Receptor 7 (HTR7) (AA 404-433), (C-Term) antibody (ABIN954739) Western blot analysis of HTR7 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/...
Background publications Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Corominas, Sobrido, Ribasés et al.: "Association study of the serotoninergic system in migraine in the Spanish population." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 1, pp. 177-84, 2009 (PubMed).

Iceta, Mesonero, Aramayona et al.: "Expression of 5-HT1A and 5-HT7 receptors in Caco-2 cells and their role in the regulation of serotonin transporter activity." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 60, Issue 1, pp. 157-64, 2009 (PubMed).

Wei, Wang, Xuan et al.: "Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 33, Issue 3, pp. 547-51, 2009 (PubMed).