APCS antibody (C-Term)

Catalog No. ABIN954752

Product Details anti-APCS Antibody

Target: APCS (Amyloid P Component, Serum (APCS))

Binding Specificity: AA 154-182, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APCS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Serum amyloid P-component.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human APCS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Alternative Name: Serum Amyloid P-Component (APCS Products)

Synonyms: PTX2 antibody, SAP antibody, Sap antibody, APCS antibody, FP antibody, SAP(FP) antibody, apcs antibody, ptx2 antibody, sap antibody, amyloid P component, serum antibody, serum amyloid P-component antibody, amyloid P component, serum protein L homeolog antibody, APCS antibody, Apcs antibody, apcs.L antibody

Background: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.Synonyms: 9.5S alpha-1-glycoprotein, APCS, PTX2, SAP

Gene ID: 325

NCBI Accession: NP_001630