SESN3 antibody (Middle Region)

Catalog No. ABIN954753

Product Details anti-SESN3 Antibody

Target: SESN3 (Sestrin 3 (SESN3))

Binding Specificity: AA 319-347, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes Sestrin-3 (Center Y335).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 319-347 amino acids from the Central region of Human Sestrin-3 Genename: SESN3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: Sestrin-3 (SESN3) (SESN3 Products)

Synonyms: cb261 antibody, sb:cb261 antibody, zgc:56722 antibody, wu:fb77c04 antibody, wu:fc41d03 antibody, wu:fd59d12 antibody, sestrin-3 antibody, sest3 antibody, SEST3 antibody, 5630400E15Rik antibody, BC003348 antibody, sestrin 3 antibody, sestrin 3 L homeolog antibody, SESN3 antibody, sesn3 antibody, sesn3.L antibody, Sesn3 antibody

Background: Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.Synonyms: SEST3

Gene ID: 143686

NCBI Accession: NP_653266