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SGIP1 antibody (SH3-Domain GRB2-Like (Endophilin) Interacting Protein 1) (N-Term)

Details for Product anti-SGIP1 Antibody No. ABIN954777, Supplier: Log in to see
Antigen
  • 3110007P09Rik
  • SGIP1alpha
  • gag
  • SH3-domain GRB2-like (endophilin) interacting protein 1
  • SGIP1
  • Sgip1
Epitope
N-Term, AA 1-30
17
10
1
Reactivity
Human, Mouse (Murine)
20
11
Host
Rabbit
20
Clonality
Polyclonal
Conjugate
This SGIP1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
18
15
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human SGIP1 Genename: SGIP1
Isotype Ig
Specificity Recognizes SGIP1 Antibody (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name SGIP1 (SGIP1 Antibody Abstract)
Background SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3, MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015])Synonyms: Endophilin-3-interacting protein, SH3-containing GRB2-like protein 3-interacting protein 1
Gene ID 84251
NCBI Accession NP_115667
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-SGIP1 antibody (SH3-Domain GRB2-Like (Endophilin) Interacting Protein 1) (N-Term) (ABIN954777) Western blot analysis using SGIP1 Antibody (N-term) Cat.-No AP53888PU-N in CHO, MDA-M...
Background publications Luke, OMeara, Rowland, Shiffman, Bare, Arellano, Longstreth, Lumley, Rice, Tracy, Devlin, Psaty: "Gene variants associated with ischemic stroke: the cardiovascular health study." in: Stroke; a journal of cerebral circulation, Vol. 40, Issue 2, pp. 363-8, 2009 (PubMed).

Uezu, Horiuchi, Kanda, Kikuchi, Umeda, Tsujita, Suetsugu, Araki, Yamamoto, Takenawa, Nakanishi: "SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26481-9, 2007 (PubMed).

Shiffman, OMeara, Bare, Rowland, Louie, Arellano, Lumley, Rice, Iakoubova, Luke, Young, Malloy, Kane, Ellis, Tracy, Devlin, Psaty: "Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 1, pp. 173-9, 2007 (PubMed).

Trevaskis, Walder, Foletta, Kerr-Bayles, McMillan, Cooper, Lee, Bolton, Prior, Fahey, Whitecross, Morton, Schwartz, Collier: "Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance." in: Endocrinology, Vol. 146, Issue 9, pp. 3757-64, 2005 (PubMed).

Simpson, Wellenreuther, Poustka, Pepperkok, Wiemann: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).