SLAMF6 antibody (C-Term)

Catalog No. ABIN954817

Product Details anti-SLAMF6 Antibody

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Binding Specificity: AA 276-305, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human CD352 / SLAMF6 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of Human SLAMF6 Genename: SLAMF6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLAMF6

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Alternative Name: CD352 / SLAMF6 (SLAMF6 Products)

Synonyms: SLAMF6 antibody, CD352 antibody, KALI antibody, KALIb antibody, Ly108 antibody, NTB-A antibody, NTBA antibody, SF2000 antibody, KAL1 antibody, KAL1b antibody, RGD1561848 antibody, SLAM family member 6 antibody, SLAMF6 antibody, Slamf6 antibody

Background: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Synonyms: Activating NK receptor, KALI, LY108, NK-T-B-antigen, NTB-A

Molecular Weight: 37345 Da

Gene ID: 114836

NCBI Accession: NP_001171643