SSR4 antibody (Middle Region)

Catalog No. ABIN954957

Product Details anti-SSR4 Antibody

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Binding Specificity: AA 97-126, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human SSR4 / TRAPD (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of Human SSR4. Genename: SSR4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SSR4

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Alternative Name: SSR4 / TRAPD (SSR4 Products)

Synonyms: TRAPD antibody, AW743063 antibody, C78062 antibody, Trap antibody, signal sequence receptor subunit 4 antibody, signal sequence receptor, delta antibody, SSR4 antibody, Ssr4 antibody

Background: SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.Synonyms: SSR-delta, Signal sequence receptor subunit delta, TRAP-delta, Translocon-associated protein subunit delta

Molecular Weight: 18999 Da

Gene ID: 6748

NCBI Accession: NP_001191455