Stanniocalcin 1 antibody (C-Term)

Catalog No. ABIN954968

Product Details anti-Stanniocalcin 1 Antibody

Target: Stanniocalcin 1 (STC1)

Binding Specificity: AA 192-221, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Stanniocalcin-1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 192-221aa) of human Stanniocalcin-1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Stanniocalcin 1

Target: Stanniocalcin 1 (STC1)

Alternative Name: Stanniocalcin 1 / STC1 (STC1 Products)

Synonyms: STC antibody, Stc antibody, stc1 antibody, MGC82280 antibody, STC1 antibody, zgc:153307 antibody, LOC777959 antibody, stanniocalcin 1 antibody, stanniocalcin 1 L homeolog antibody, stanniocalcin 1 S homeolog antibody, STC1 antibody, Stc1 antibody, stc1.L antibody, stc1.S antibody, stc1 antibody, LOC777959 antibody

Background: The STC1 gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.Synonyms: STC, STC-1, Stanniocalcin-1

Gene ID: 6781

NCBI Accession: NP_003146

Pathways: Hormone Activity