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STEAP3 antibody (C-Term)
STEAP3
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-STEAP3 Antibody
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Target
See all STEAP3 Antibodies
STEAP3
(STEAP Family Member 3, Metalloreductase (STEAP3))
Binding Specificity
All epitopes for STEAP3 antibodies
AA 440-470, C-Term
Reactivity
All reactivities for STEAP3 antibodies
Human
Host
All hosts for STEAP3 antibodies
Rabbit
Clonality
All clonalities for STEAP3 antibodies
Polyclonal
Conjugate
All conjugates for STEAP3 antibodies
This STEAP3 antibody is un-conjugated
Application
All applications for STEAP3 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to STEAP3.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human STEAP3
Isotype
Ig Fraction
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Discover our top product STEAP3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for STEAP3
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Target
STEAP3
(STEAP Family Member 3, Metalloreductase (STEAP3))
Alternative Name
STEAP3 / TSAP6 (STEAP3 Products )
Background
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.Synonyms: Dudulin-2, Metalloreductase STEAP3, STEAP-3, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, pH yde
Molecular Weight
54601 Da
Gene ID
55240
NCBI Accession
NP_001008410
Pathways
Transition Metal Ion Homeostasis
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