STXBP2 antibody (C-Term)

Catalog No. ABIN954993

Product Details anti-STXBP2 Antibody

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Binding Specificity: AA 439-469, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to STXBP2.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 439-469 amino acids from the C-terminal region of human STXBP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Alternative Name: STXBP2 / UNC18B (STXBP2 Products)

Synonyms: zgc:85807 antibody, FHL5 antibody, Hunc18b antibody, MUNC18-2 antibody, UNC18-2 antibody, UNC18B antibody, pp10122 antibody, C79054 antibody, Munc-18-2 antibody, Munc-18b antibody, Munc18b antibody, Sxtbp2 antibody, Sxtp2 antibody, Unc18-2 antibody, Unc18b antibody, muSec1 antibody, MUNC-18-2 antibody, syntaxin binding protein 2 antibody, stxbp2 antibody, STXBP2 antibody, Stxbp2 antibody

Background: STXBP2 is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.Synonyms: Syntaxin-binding protein 2, UNC-18B, UNC18-2, unc-18 homolog 2, unc-18 homolog B

Molecular Weight: 66453 Da

Gene ID: 6813

NCBI Accession: NP_001120868

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis