SGSH antibody (C-Term)

Catalog No. ABIN954998

Product Details anti-SGSH Antibody

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Binding Specificity: AA 427-457, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Recognizes Sulphamidase / SGSH (C-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 427~457 amino acids from the C-terminal region of Human SGSH. Genename: SGSH

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: Sulphamidase / SGSH (SGSH Products)

Synonyms: HSS antibody, MPS3A antibody, SFMD antibody, 4632406A19Rik antibody, N-sulfoglucosamine sulfohydrolase antibody, N-sulfoglucosamine sulfohydrolase (sulfamidase) antibody, SGSH antibody, Sgsh antibody

Background: SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.Synonyms: HSS, N-sulphoglucosamine sulphohydrolase, Sulfoglucosamine sulfamidase

Gene ID: 6448

NCBI Accession: NP_000190

Pathways: Glycosaminoglycan Metabolic Process